Home › Forums › Stay Dirty Lounge › Service and Repair Questions Answered Here › p0301 misfire in cylinder 1? › Re: p0301 misfire in cylinder 1? November 8, 2012 at 2:08 am #475136 EricTheCarGuyKeymaster You might start with a power balance test to see if indeed it’s cylinder #1 that’s the problem. After that the next step is to find out if it’s an issue with spark delivery, fuel delivery, or a mechanical issue.